Lack of unsaturated fat triggers numerous sclerosis study finds 2

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The study finds The strange resistant framework reaction that causes different sclerosis (MS) by assaulting and harming the Central Nervous System can be set off by the absence of a particular unsaturated fat in tissues, another examination recommends.

The finding, distributed in The Journal of Clinical Investigation, proposes that dietary change may help treat a few people enduring the immune system sickness.

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We’ve known for a while that both genetics and environment play a role in the development of MS,” said senior author David Hafler, Professor at Yale University in the US.

This paper suggests that one of the environmental factors involved is diet,” Hafler added by study

Fat tissues in patients diagnosed with MS lack normal levels of ‘oleic acid’, a monounsaturated fatty acid found in high levels in cooking oils, meats (beef, chicken, and pork), cheese, nuts, sunflower seeds, eggs, pasta, milk, olives, and avocados, according to the study.

This lack of oleic acid leads to a loss of the metabolic sensors that activate T cells, that mediate the immune system’s response to infectious disease, the team found.

Without the suppressing effects of these regulatory T cells, the immune system can attack healthy Central Nervous System cells and lead to vision loss, pain, lack of coordination, and other debilitating symptoms of MS.

When researchers introduced oleic acid into the fatty tissues of MS patients in laboratory experiments, levels of regulatory T cells increased, they found.

The researcher had earlier noted that obesity triggers unhealthy levels of inflammation and is a known risk factor for MS, an observation that led him to study the role of diet in MS.

He stressed, however, that more study is necessary to determine whether eating a diet high in oleic acid can help some MS patients.

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